Skip to content

Use Cases

Phase 2 (Months 12–18) implements three science use cases that demonstrate the MESA prototype against real research workflows. Each use case delivers a reproducible workflow with a DOI by Month 18.

Use case Domain Lead WBS
UC1 — Agentic Discovery + Multi-Omics Bioinformatics — genomic / transcriptomic / proteomic / metabolomic Roberts, Chism, Swetnam 5.0
UC2 — Geospatial + EHT Geospatial analytics + sub-PB Event Horizon Telescope pipeline Chan 5.0
UC3 — IoT / Edge Precision-agriculture sensor networks + 5G/6G edge Chen, GRA 4 5.0

Why these three?

The use cases are chosen to stress-test all three innovation goals:

Goal Stressed by
Goal 1 — Lakehouse UC1 multi-omics joins; UC2 spatial-temporal queries; UC3 high-frequency sensor streams
Goal 2 — Data Mesh UC1 cross-institution genomic data; UC2 EHT collaboration zones; UC3 partner-farm zones
Goal 3 — Agentic AI UC1 hypothesis generation; UC2 pipeline orchestration; UC3 anomaly triage

Reproducibility commitment

Every use-case workflow is published as:

  1. Open-source code under permissive license on GitHub.
  2. Reproducible IaC templates so the workflow can be re-run on any ACCESS-CI / CyVerse-aligned cluster.
  3. Notebooks and tutorials integrated with the Educator Fellows program.
  4. A DOI issued through CyVerse's DataCite service.